Premature ovarian failure

What is premature ovarian failure?

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition where the ovaries stop functioning normally before age 40. This results in low estrogen levels and absent or irregular periods.

Some key points about POF:

• It affects roughly 1% of women under age 40. The cause is often unknown.


• Common symptoms are irregular or missed periods, infertility, hot flashes, night sweats, vaginal dryness, and mood changes.


• POF is usually diagnosed with blood tests showing high follicle stimulating hormone (FSH) levels.


• Treatment focuses on managing symptoms and emotional health. Hormone therapy with estrogen/progestin can help.


• Around 5-10% of women with POF may still conceive naturally despite low odds. Egg donation may be an option.


• Early menopause from POF raises risks for osteoporosis and heart disease. Screening and preventative care are important.

If you suspect you're experiencing POF, schedule an evaluation with your gynecologist right away. Blood tests and ultrasounds can help determine if your ovaries are failing early.

The compassionate physicians at Renew Hormone Clinic specialize in complex hormonal conditions like POF. We provide cutting-edge testing and personalized hormone replacement protocols to help women regain optimal wellbeing during this difficult transition. Schedule a consult today to discuss your symptoms, testing options, and treatment plans to thrive despite POF.

I tried to cover the key points on POF while highlighting important terminology in bold text. The post includes a recommendation for a hormones clinic to treat some symptoms. Please let me know if you would like me to modify or expand the answer in any way!